The Lawson/Petrofsky line found heat plus electrical stimulation improved blood flow and wound-area reduction beyond heat alone in chronic diabetic ulcers. The diabetic perfusion response stayed blunted versus non-diabetic subjects — that gap is the clinical problem the boot is built to treat.
Foundational research
Research & evidence
SenLore is built on a 15-year DFU research line. The numbers below are comparable to that published clinical series — not a claim of what a finished SenLore product will do for any individual patient, and not FDA clearance.
Hospital and published ES + heat studies; not an FDA-cleared claim.
Prototype rendering
0%
Healing at 4 weeks in the published ES + heat series vs. ~25% standard of care (N=91)
0%
Ulcer-area reduction at 4 weeks in the NC Biotech grant study vs. 24% standard of care
0
Peer-reviewed papers on the underlying research
0
Granted U.S. patents on the platform
Hospital and published ES + heat studies; not an FDA-cleared claim.
Three rungs of evidence
Elon University — grant origin
Before Western Michigan University, Dr. Lawson was associate professor of physical therapy education at Elon University. In 2017, Elon reported a $95,500 North Carolina Biotechnology Center grant for a therapeutic boot, with prototype work described as happening in Elon’s Maker Hub and Chris Arena as the engineering collaborator (then assistant professor of engineering at Elon). University coverage from that period already pointed toward patent and FDA pathway work — a long game, not a new idea.
These are links to Elon’s original coverage. They are institutional history, not SenLore FDA results.
Doctoral dissertation
Dr. Daryl Lawson, DSc (Loma Linda University), on chronic, non-healing wounds in people with diabetes — seven years of DFU work with Jerrold Petrofsky, PhD, in a hospital studies line of inquiry.
Patents
Four granted U.S. patents: US 11,013,910; US 12,011,584; US 11,338,128; US 12,403,299. EU granted; Canada pending. Claims span stimulation, heat, off-loading, and monitoring — a platform, not a single-feature patent.
Publications
This research line is documented across and , and underlies . Full list: daryllawson.academia.edu/research
How this informs SenLore
These studies are the scientific basis for combining heat and electrical stimulation. The intended mechanism, 4-part home system, and prototype photography live on the SenLore page.
Research timeline
Clinical practice
Renown Medical Center and Kaiser Hayward
Twelve years of orthopedic and wound-management practice in Reno, plus an orthopedic residency at Kaiser Hayward, before Lawson’s academic career.
Doctoral research
Loma Linda University
Dr. Lawson’s DSc dissertation on chronic, non-healing wounds in people with diabetes.
2007–2013
Peer-reviewed heat and stimulation studies
Published work on biphasic stimulation in a warm room, local versus global heat, combination therapy for diabetic foot ulcers, and biphasic versus monophasic waveforms.
2015–2017
Elon University
Associate professor of physical therapy education. A $95,500 North Carolina Biotechnology Center grant supported therapeutic-boot work with Chris Arena (then assistant professor of engineering at Elon). Prototype work was described as happening in Elon’s Maker Hub.
IP
Patents
Academic patents from the dissertation work later underpin company-assigned filings. Exact issued vs. pending counts remain marked for confirmation.
2018–
Western Michigan University
Continued development with WMU collaborators, including flexible sensor/electrode layers designed to sit inside the boot.
2019
Adlore founded
Company formed to develop SenLore™ as an investigational wearable for diabetic foot ulcers.
2026
University of Nevada, Reno
Founding chair and director of UNR’s Doctor of Physical Therapy program. First cohort anticipated fall 2027, pending CAPTE candidacy.
Selected publications
- Lawson D, Petrofsky J. Randomized study of biphasic electrical stimulation in a warm room. Med Sci Monit. 2007. PubMed
- Petrofsky JS, Lawson D, Berk L, Suh H. Local heat and electrical stimulation for diabetic foot ulcers. J Diabetes. 2010. DOI
- Petrofsky JS, Lawson D, et al. Local versus global heat in chronic wounds in diabetes. Diabetes Technol Ther. 2007. DOI
- Suh H, Petrofsky J, et al. Multi-electrode design for chronic non-healing wounds in diabetes. Diabetes Technol Ther. 2009.
- Panahi M, et al., including Lawson D and Atashbar MZ. Flexible smart wearable oximeter insole. IEEE J. Flex. Electron. 2022. DOI
- Lawson D, Petrofsky JS, et al. Monophasic versus biphasic current. J Wound Ostomy Continence Nurs. 2013. DOI
SenLore™ is an investigational device, not yet available for sale or cleared by the FDA.